LETTERS TO THE EDITOR Comments on ‘‘Chromosome Intrachanges and Interchanges Detected by Multicolor Banding in Lymphocytes: Searching

Johannes et al. (1) recently presented interesting new data on the LET dependence of intrachromosomal aberration yields, which may be compared with earlier theoretical calculations and experimental results. Specifically, Johannes et al. reported that their measured ratios of intrachromosomal to interchromosomal aberrations were independent of LET, in contrast to some in vitro measurements (2), in vivo results (3), and theoretical expectations (4, 5). We suggest there may be two reasons for this discrepancy: